Plinest in Penang | CANVAS Medical Clinic
The Italian polynucleotide from Mastelli — the laboratory that pioneered PN technology. Physician-administered at Gurney Walk, George Town, Plinest bio-restructures ageing, damaged or thinning skin from within: repair, elasticity and hydration, including the delicate eye area.
What is Plinest?
Plinest is a polynucleotide (PN) injectable from Mastelli of Italy — the laboratory whose research effectively created the polynucleotide category. Highly purified PN fragments signal the skin to repair itself: stimulating fibroblasts, supporting the extracellular matrix, improving hydration and restoring elasticity to skin that has thinned or weathered.
At CANVAS Medical Clinic in George Town, Penang, Plinest anchors bio-restructuring programmes for ageing, dull or fragile skin — with Plinest Eye offering a dedicated formulation for dark-circle-prone, crepey under-eye skin, and the standard formulation treating face, neck and beyond.
How it works
- Consultation & variant selection. Your physician assesses skin condition and the eye area, selecting Plinest, Plinest Eye or a combination.
- Treatment session. Polynucleotides are microinjected evenly across the treatment area. Numbing cream keeps the session comfortable.
- Bio-restructuring — weeks 1 to 4. PN signalling stimulates fibroblasts and matrix repair; hydration, elasticity and resilience improve progressively.
- Course & maintenance. Three to four sessions, two to three weeks apart, complete a course; maintenance is typically every six to twelve months.
Benefits
From the PN pioneers
Mastelli's polynucleotide research defined the category — Plinest is its direct product.
True biological repair
Signals the skin to rebuild itself rather than masking symptoms.
Dedicated eye formulation
Plinest Eye treats crepey, dark-circle-prone under-eye skin appropriately gently.
Elasticity restored
Thinning, fragile or weathered skin regains bounce and resilience.
Beyond the face
Neck and selected body areas respond to the same bio-restructuring logic.
Complements everything
PN repair layers naturally under boosters, biostimulators and energy treatments.
Who it's for
Plinest may be suitable if you:
- Have thinning, fragile or weathered skin that needs genuine repair
- Notice crepiness or dark-circle-prone under-eye skin
- Want a regenerative foundation before other aesthetic work
- Prefer biological repair over volumising or masking
- Are managing early ageing on the neck as well as the face
- Value products with deep clinical heritage
Plinest is not suitable during pregnancy or breastfeeding, with fish allergy (discuss with your physician), or over active skin infection. Suitability is always confirmed at consultation.
Plinest vs Rejuran
Both are polynucleotide therapies with the same core mechanism — PN fragments signalling skin repair. Rejuran is the Korean interpretation, Plinest the Italian original from Mastelli's research. Formulation nuances differ, and clinics often observe slightly different textures and protocols between them.
At CANVAS both are on formulary, along with Rejuran's scar and eye variants. Your physician will recommend the PN — or sequence — that fits your skin, rather than defaulting to one brand.
Why CANVAS
At CANVAS Medical Clinic, Plinest is administered only by qualified, LCP-certified physicians using authentic, registered product. PN therapy rewards correct depth and honest course-setting — our physicians manage both directly.
We are located at Gurney Walk in the heart of George Town, with covered parking at Gurney Walk and Gurney Plaza. Walk-ins are welcome but we recommend booking in advance.
- LCP-certified physicians administer every Plinest treatment
- Licensed, registered and authentically sourced products only
- Honest assessment — we'll tell you if another treatment suits you better
- Full injectables formulary under one roof for true combination planning
- Central Gurney Walk location with easy covered parking
Plinest in Penang, answered.
Care led by our physicians
Your Plinest treatment at CANVAS is planned and carried out by qualified, LCP-certified doctors registered with the Malaysian Medical Council — care is never delegated to unsupervised operators. Meet the physicians behind your treatment:
- LCP CertifiedPhysician-led care
- MMC RegisteredQualified doctors
- Authentic ProductsLicensed & registered
- Open Daily10am – 10pm
Related treatments
Explore other physician-led treatments at our Gurney Walk clinic in George Town, Penang.
From our patients
Read our reviews on Google →Considering Plinest in Penang?
Book a consultation at our Gurney Walk clinic. Our physicians will assess what your skin needs repaired, and whether Plinest — or another point in our regenerative formulary — is the right foundation.
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